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Cryptosporidiosis is a diarrheal disease caused by microscopic parasites of the genusCryptosporidium. Both the disease and the parasite are commonly known as "Crypto."
Many species of Cryptosporidium exist that infect humans and a wide range of animals. The parasite is protected by an outer shell that allows it to survive outside the body for long periods of time and makes it very resistant to chlorine disinfection.
While this parasite can be transmitted in several different ways, water is a common method of transmission andCryptosporidium is one of the most frequent causes of waterborne disease (drinking water and recreational water) among humans in the United States.
The Virusys Cryptosporidium IMS Beads (Crypto IMS Beads) have been developed for the immunomagnetic separation (IMS) of Cryptosporidium spp. oocysts from a wide range of sample matrices.
The high sensitivity and specificity of the Crypto IMS Beads results from the covalent attachment of a high affinity monoclonal antibody developed against an epitope on the wall of Cryptosporidium oocysts. When combined with the Virusys IMS Assay Buffer (IMS206:BFR) and IMS Wash Buffer (IMS206:Wash), Cryptosporidium oocysts can be efficiently isolated and enumerated by a variety of techniques including, but not limited to immunofluorescent antibody (IFA) staining and PCR.
Human Cytomegalovirus is a herpesvirus of the betaherpesvirinae subfamily. The members of this subfamily tend to have a restricted host range, slow spread in cell culture and a long growth cycle as compared to Herpes Simplex Virus.
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An open reading frame or ORF is a portion of an organism's genome which contains a sequence of bases that could potentially encode a protein. In a gene, ORFs are located between the start-code sequence (initiation codon) and the stop-code sequence (termination codon).
CMV Assays and Components
Monoclonal and polyclonal antibodies to proteins of the virus as well as non-structural regulatory and assembly proteins. All have been evaluated for IFA and western blot function.
Infected cell extracts, nuclear extracts, density gradient purified virus, glycoprotein fractions and more. Many are characterized with a full SDS-PAGE and western blot profile.
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