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mOct4 Adenovirus (Mouse)

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mOct4 Adenovirus (Mouse)

商品詳情參考文獻相關資料

	Print Version
Vector	pAdeno
Promoter	CMV
Insert	mOct4
Picture
Organism	Mouse
Accession #	P20263
Alias	Pou5f1, Oct-3, Oct-4, Otf-3, Otf3
Protein Type	Wild Type
Protein Family	Belongs to the POU transcription factor family. Class-5 subfamily.
Functions	Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Forms a trimeric complex with SOX2 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency. The product can be used in combination with other iPSC factor for the induction of iPSC reprogramming.
Cell Types	Expressed the totipotent and pluripotent stem cells of the pregastrulation embryo.
Protein Location	Nucleus
Gene Type	cDNA
Purification	By Ion-Exchange column.
Quality Control	By sequencing and Western blot analysis of transgene expression in transduced cells. Functional test includes iPSC reprogramming.
Titer	>1x10⁶pfu/mL
Storage	10 mM Tris-HCl, pH 8.0
Shipping	High titer adenoviruses are shipped with dry ice and low titer adenoviruses are shipped with ice packs. For long term storage, it is recommended to store the viruses at -80°C in small aliquots to avoid repeated freeze-thaw cycles.
Notes	For Research Use Only, not for therapeutic or diagnostic purposes.