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上海拜力生物科技公司
Tel:400-968-7988    021-33779008
Recombinant Human NRG1
品牌:Abmgood
貨號(hào):Z101629
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Recombinant Human NRG1

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Alternative Names Acetylcholine receptor-inducing activity, ARIA, Breast cancer cell differentiation factor p45, Glial growth factor, Heregulin, HRG, Neu differentiation factor, Sensory and motor neuron-derived factor
Recombinant Human Neuregulin-1 Beta (NRG1)
Description Neuregulins are EGF-like growth and differentiation factors that signal through tyrosine kinase receptors of the ErbB family. The ErbB2 and ErbB4 receptors cooperate in transmission of neuregulin-1 signals in the heart, whereas ErbB2 and ErbB3 cooperate in neural crest cells.
Gene Symbol NRG1
Gene ID 3084
Accession No. Q02297
Source E. coli
Appearance Lyophilized Powder
Molecular Weight 7.0 kDa
Endotoxin Level <1.0 EU/μg of recombinant protein as determined by the LAL method.
Purity >95% as determined by SDS-PAGE
Bioactivity The ED(50) was determined by the dose-dependent proliferation of human MCF-7 cells was found to be < 0.3 ng/mL, corresponding to a specific activity of 2.0 x 10^6 Units/mg.
Formulation Recombinant Neuregulin-1 was lyophilized from a 0.2 μm filtered 10mM PB, pH 7.0, containing 2% mannitol, 0.5% HSA.
Reconstitution A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.
Storage The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.
Usage For research use only. Not for diagnostic or therapeutic use.
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