Supplied in Phosphate Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 50% Glycerol.
Storage:
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Target
Function:
Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins during skeletal muscle atrophy. Recognizes TERF1.
Tissue Specificity:
Specifically expressed in cardiac and skeletal muscle.
Cellular Location:
Cytoplasm. Nucleus.
Shuttles between cytoplasm and the nucleus.
Database Links:
Entrez Gene: 114907?Human
Entrez Gene: 67731?Mouse
Entrez Gene: 171043?Rat
Omim: 606604?Human
SwissProt: Q969P5?Human
SwissProt: Q9CPU7?Mouse
SwissProt: Q91Z62?Rat
Unigene: 403933?Human
Unigene: 25683?Mouse
Unigene: 292042?Mouse
Unigene: 72619?Rat
Synonyms:
4833442G10Rik Antibody
AI430017 Antibody
Atrogin 1 Antibody
Atrogin-1 Antibody
ATROGIN1 Antibody
Atrophy gene 1 Antibody
F box only protein 32 Antibody
F-box only protein 32 Antibody
F-box protein 32 Antibody
Fbx32 Antibody
FBX32_HUMAN Antibody
fbxo25 Antibody
FBXO32 Antibody
FLJ32424 Antibody
MAFbx Antibody
MGC108443 Antibody
MGC137646 Antibody
MGC33610 Antibody
Muscle atrophy F box Antibody
Muscle atrophy F box protein Antibody
Muscle atrophy F-box protein Antibody
Information:
Target information shown above is from the UniProt Consortium.