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Anti-FBL Antibody
品牌：Antibodies
貨號(hào)：
規(guī)格：100μg
貨期：
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Anti-FBL Antibody
商品詳情 參考文獻(xiàn) 相關(guān)資料
Name: Anti-FBL Antibody
See all FBL primary antibodies
Description: Goat polyclonal antibody to FBL.
Applications: ELISA, WB
Reactivity: Human
Immunogen: Synthetic peptide corresponding to Human FBL (internal region).
Sequence: CRGKEDALVTKN
Host: Goat
Clonality: Polyclonal
Isotype: IgG
Conjugate: Unconjugated
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 100 μg at 0.5 mg/ml.
Product Form: Liquid
Formulation: Supplied in Tris Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 0.5% BSA.
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Function: S-adenosyl-L-methionine-dependent methyltransferase that has the ability to methylate both RNAs and proteins. Involved in pre-rRNA processing by catalyzing the site-specific 2'-hydroxyl methylation of ribose moieties in pre-ribosomal RNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA. Also acts as a protein methyltransferase by mediating methylation of 'Gln-105' of histone H2A (H2AQ104me), a modification that impairs binding of the FACT complex and is specifically present at 35S ribosomal DNA locus (PubMed:24352239).
Sequence Similarities: Belongs to the methyltransferase superfamily. Fibrillarin family.
Post-Translational Modification: By homology to other fibrillarins, some or all of the N-terminal domain arginines are modified to asymmetric dimethylarginine (DMA).
Cellular Location: Nucleus > Nucleolus.

Fibrillar region of the nucleolus.
Database Links:
  • Entrez Gene: 2091?Human
  • Omim: 134795?Human
  • SwissProt: P22087?Human
  • Unigene: 299002?Human
    		•
    Synonyms:
  • 34 kD nucleolar scleroderma antigen Antibody
  • 34 kDa nucleolar scleroderma antigen Antibody
  • Fbl Antibody
  • FBRL_HUMAN Antibody
  • FIB Antibody
  • FIB1 Antibody
  • Fibrillarin Antibody
  • FLRN Antibody
  • Histone-glutamine methyltransferase Antibody
  • Nop1p Antibody
  • RNA U3 small nucleolar interacting protein 1 Antibody
  • RNU3IP1 Antibody
  • rRNA 2' O methyltransferase fibrillarin Antibody
  • rRNA 2'-O-methyltransferase fibrillarin Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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